Celiac Disease Versus Gluten Sensitivity?

In a new study  in BMC Medicine (A Sapone et al., published online March 9, 2011), researchers examined the difference between gluten-associated disorders celaic disease and gluten sensitivity, at the molecular level.  They found differences in levels of intestinal permeability and responses elicited from the immune system.

Stating that the study provides the first scientific evidence of a different mechanism leading to gluten sensitivity, the researchers say the differences contribute to “the characterization of gluten sensitivity as a condition associated with prevalent gluten-induced activation on innate, rather than adaptive immune responses in the absence of detectable changes in mucosal barrier function.”

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