Insulin resistance comes in picture when the total amount of insulin produced by the body (pancreas), proves to be insufficient to maintain normal blood glucose level. Extra insulin may need to break down glucose in order to release energy. In about 1/3 of the cases blood cells resist to even high level of insulin. Insulin resistance is mostly associated with high Triglycerides and low HDL, hypertension, cardiovascular disease and other such abnormalities. It is in these abnormalities that we find the insulin resistance syndrome. Few people sometimes suffer from various symptoms and conditions. It is thus believed that diabetes and other problems go hand in hand.
If one of your siblings or parents has been diagnosed with diabetes, or there is a previous history of diabetes during pregnancy, history of polycystic ovary syndrome, diabetes that is not high enough than the blood sugar level, overweight or obese can be causes of diabetes. Insulin resistance can be often seen in the following conditions like the metabolic syndrome, obesity, pregnancy, infection or severe illness, stress during steroid use.
Insulin resistance tends to run in families and ethnicity, which makes us know that genes are partly responsible. Excess weight also contributes to insulin resistance because too much fat interferes with muscles ability to use insulin. It is seen that a sedentary lifestyle, such as excessive caloric intake and inadequate exercise is the most important factor which can be controlled out. In most cases, the effect of insulin resistance on the body is subtle and takes many years in developing further. It first begins with hyperglycemia and over time, hyperglycemia can progress and become diabetes type 2.